Additionally, the study's findings may broadly influence drug discovery efforts targeting RNA-binding proteins. "Our structural insights into ADAR1 provide a solid foundation for designing small ...

"It likely sequesters other RNA-binding proteins, creating an even more toxic environment for cancer cells." Further studies will refine ASO-based therapies and explore their delivery to tumors.

When the coat proteins come into contact after binding the RNA hairpins, these luciferase fragments, along with the enzyme’s substrate furimazine, join together—and the probe lights up.

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns ...