The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

Researchers at São Paulo State University (UNESP) in Brazil have identified a robust set of genetic markers associated with ...

This article explores a new therapeutic approach for rheumatoid arthritis (RA) using a combination of triptolide and ...

Figure 1. The involvement of ROS and products of ROS-dependent oxidation in cellular signaling network. The main sources of ROS (marked with blue arrows) include mitochondria, chloroplast, NADPH ...

This led to the identification of AcrVIB1, the first anti-CRISPR protein targeting the Cas13b nuclease," says HIRI department head Prof. Chase Beisel, who led the study together with the ...

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Summary: Researchers have identified unique RNA structures called G-quadruplexes (G4s) that promote harmful α-synuclein protein aggregation linked to neurodegenerative diseases like Parkinson’s.

This target centers on RNA regulation, which, when disrupted in humans, is often linked to neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease, as well as many types of cancer.

What the RNA [COVID] vaccines do is they give the code for the spike protein of the COVID-19 virus. The body then recognizes that as a foreign protein and makes an immune response that preps the ...

RNA transcription is the genomic process in which a cell produces a duplicate of a gene’s DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department ...