Abstract: Recent studies have demonstrated that miRNA expression dysregulation is closely related to the occurrence of various diseases; thus, miRNA-based drug development strategies have received ...

RALY was identified in the spliceosome complex and in the Drosha microprocessor complex. The m 6 A modification is found to alter RNA structure to enhance HNRNPC binding, and HNRNPA2B1 could bind to ...

然而，肿瘤细胞能够通过多种机制逃避 IFN-γ 介导的免疫激活，导致免疫治疗失败。 Argonaute 2（AGO2）是 Argonaute 家族的关键成员，作为微小 RNA（miRNA）传感器，可对 miRNA 库的动态变化迅速做出反应，并靶向下游 mRNA 发挥多种作用。AGO2 在肿瘤免疫治疗中的作用 ...

癌症干细胞（CSCs）来源的外泌体 miRNA 在肿瘤转移前微环境的形成、血管生成以及肿瘤转移过程中发挥着至关重要的作用。深入研究 CSCs 来源的外泌体 miRNA 的作用机制，不仅有助于我们进一步理解癌症转移的生物学过程，还为开发针对癌症转移的新型治疗策略 ...

Argonaute 2（AGO2）是Argonaute家族的重要成员，它作为微RNA（miRNA）传感器，能对miRNA池的动态变化迅速做出反应，并靶向下游mRNA，发挥不同的作用。

Luciferase activity was evaluated 24 h after transfection (Promega, E2920). The RIP solution containing magnetic beads containing either mouse IgG or human anti-Ago2 antibody was added to cell lysates ...

Homeland Security Secretary Kristi Noem drew outrage when she sported a Rolex watch reported to cost $50,000 when visiting the El Salvadorian mega-prison known as CECOT this month. Civil rights ...