LncRNAs and circRNAs are key regulators of gene expression, influencing disease mechanisms and offering potential as ...

They showed that shutting down a damaged copy of a gene called a microRNA (miRNA) enabled ... Novel Genome Editing Approach Restores Hearing in Adult Preclinical Models With Genetic Deafness July ...

Former talk show host Wendy Williams took steady aim at her court-appointed guardianship in an interview with "The View" ...

帕金森病（Parkinson’s disease，PD）是一种慢性神经退行性疾病，其特征为多巴胺能神经元逐渐退化，进而引发一系列导致机体功能障碍的运动和非运动症状。尽管研究取得了一定进展，但 PD 的分子机制仍不明确，有效的生物标志物和治疗靶点也十分有限。近期研究表明，线粒体功能障碍和细胞代谢失调在 PD 的发病机制中起着核心作用。本研究通过计算机模拟和体外分析，探究了与线粒体功能和代谢途径相关的 ...

A gene regulatory network is a set of genes, or parts of genes, that interact with each other to control a specific cell function. Gene regulatory networks are important in development ...

结直肠癌（CRC）危害大，研究人员探究线粒体编码环状 RNA SCAR/mc-COX 2 ，发现其或为抑癌因子和诊断标志物。 肿瘤微环境（Tumor Microenvironment，TME）在 CRC 的发展中起着关键作用，其中线粒体功能障碍引发的肿瘤代谢重编程，即 Warburg 效应，尤为突出。肿瘤细胞通过这种效应改变能量产生方式，同时生成活性氧（Reactive Oxygen ...

Mar. 10, 2025 — Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in ...

Mini-brains, or brain organoids, are revolutionizing neuroscience by modeling diseases and drug responses, offering insights ...