Scientists from the Massachusetts Institute of Technology (MIT) say they have developed a simpler process for messenger RNA (mRNA) purification based on continuous precipitation. According to ...

Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, ...

The promise of mRNA technology seemed boundless after the success of the coronavirus vaccines, but Robert F. Kennedy Jr. has singled it out for scrutiny, clouding its prospects.

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component ...

Co-delivery of SpyC-mi3 and Pfs25-SpyT results in assembled particles displaying Pfs25 at high density. Credit: Nature Nanotechnology (2025). DOI: 10.1038/s41565-025-01889-1 ...

Smart mRNA drugs listen to the body, adjusting protein production based on disease-related signals by University of Osaka edited by Lisa Lock, reviewed by Robert Egan Editors' notes ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

More information: An Il12 mRNA-LNP adjuvant enhances mRNA vaccine–induced CD8 T cell responses, Science Immunology (2025). DOI: 10.1126/sciimmunol.ads1328 ...

Some notable examples of personalized mRNA products include Gritstone bio’s GRANITE and Moderna’s vaccine mRNA-4157, which are expected to enter the market in Q2 2027 and Q3 2030, respectively.

Using mRNA to stop HIV from hiding away in white blood cells could be the key to developing a way to eradicate the infection, rather than simply managing viral levels in the body. The tantalising ...

Instead of extracting T-cells and engineering them in a lab, researchers have delivered mRNA directly into circulating immune ...

Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...