An evolutionarily conserved micropeptide, Sertm2, encoded by the lncRNA A730046J19Rik, promotes Etv4 + motor neuron subtype specification by GDNF, proper neurite development, and motor function.

It offers a valuable reference point for non-pharmacological intervention strategies for the comprehensive treatment of fibrotic diseases. Graphical Abstract. Exercise alleviates tissue fibrosis ...

Our study characterizes one of the first lncRNA-derived micropeptides involved in neuronal physiology. This study identifies and characterizes SERTM2, a micropeptide derived from a lncRNA (lncMN3), ...

在HCC中，肿瘤细胞能通过复杂的机制抑制免疫系统的功能从而实现免疫逃逸；长非编码RNA（lncRNA）是一类不编码蛋白质的RNA分子，近年来其被发现 ...

Atherosclerosis is characterized by the accumulation of fatty and fibrotic plaques, which preferentially develop at curvatures and branches along the arterial trees that are exposed to disturbed flow.

LncRNAs have shown significant association with the events occurring towards proliferation, regulating key events in dividing cells, and dysregulation of lncRNA transcriptome affects normal cellular ...