The N-terminal ATP-dependent ligase domain belongs to the covalent nucleotidyltransferase enzyme superfamily that includes classic RNA/DNA ligases and mRNA capping enzymes. We’ve shown that: (i) each ...

but little is known about the fidelity of transcriptional initiation by RNA polymerase II in vivo. I suggest that ∼90% of Pol II initiation events in yeast represent transcriptional noise ...

Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public Domain) Uracil was first discovered in 1900 by the Italian chemist Alberto Ascoli ...

It is compatible with cultured animal cells, tissues, blood, bacteria, yeast, fungi, and plants. Both total RNA and proteins are column-purified in under 25 minutes using a single column.

Additionally, it highlights the crucial roles of enzymes and nucleic acids (DNA and RNA) in synthesizing proteins and regulating cellular functions. Ultimately, the interplay of these processes ...