Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

Purdue University scientists have identified the Supinoxin small-molecule drug as a possible new therapy for small-cell lung ...

(NASDAQ: EXOZ) (“eXoZymes”) - a pioneer of AI-engineered enzymes that can transform sustainable feedstock into nutraceuticals ...

The MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Sciences, Victoria University of Wellington, P.O. Box 600, Wellington 6140, New Zealand ...

This pathway, or others like it, could explain why some inheritable traits between generations can’t be explained exclusively via DNA and RNA. "There are a lot of traits and disorders that we ...

结果发现硫酸乙酰肝素蛋白聚糖（HSPGs）等参与 LNP 摄取等过程，TRIM25 可抑制 mRNA，N 1 - 甲基假尿苷修饰能逃避其抑制。该研究为 RNA 免疫和疗法提供新思路。 外源性核糖核酸（RNAs），包括治疗性信使核糖核酸（mRNAs）和病毒核糖核酸，要进入细胞并合成蛋白质 ...

Plasmids are most commonly found in bacteria, providing them with advantages such as antibiotic resistance. However, the plasmid present in many yeast species does not provide any known benefit to ...

Candida auris, a type of yeast that spreads mostly in hospitals and senior care centers, can cause severe illness and death. Drug-resistant fungal infections like C. auris have been increasing ...

AIRNA, a transatlantic RNA editing biotech, is prepping to launch its lead asset into clinical trials with fuel from a $155 million series B fundraise. The round was led by Venrock Healthcare ...

Airna, a biotechnology startup developing RNA editing treatments, said Tuesday it raised $155 million in a Series B round that will help propel its lead program in alpha-1 antitrypsin deficiency into ...

中国科学院分子细胞科学卓越创新中心陈玲玲研究组揭示了双链RNA依赖的蛋白激酶R（PKR）在阿尔茨海默病（AD）发生与进展过程中异常激活的分子病理特征，开发了基于具有分子内短双链结构环形RNA（ds-cRNA）抑制PKR异常激活的策略。 AD是以淀粉样蛋白（Aβ ...