Study unravels the mysteries of actin filament polarity Date: June 8, 2023 Source: University of Pennsylvania School of Medicine Summary: An electron microscopy study revealed key details of actin ...

Molecular mechanism of actin filament elongation by formins. Science, 2024; 384 (6692) DOI: 10.1126/science.adn9560; Cite This Page: MLA; APA; Chicago; Max Planck Institute of Molecular Physiology.

Actin is a highly abundant protein that controls the shape and movement of all our cells. Actin achieves this by assembling into filaments, one actin molecule at a time. The proteins of the formin ...

Dynamic networks of protein filaments give shape to cells and power cell movement. Learn how microtubules, actin filaments, and intermediate filaments organize the cell.

Actin filaments — protein structures critical to living movement from single cells to animals — have long been known to have polarity associated with their physical characteristics, with growing ...

What was seen in the Arp2/3 complex, Nolen said, will help to understand precisely how actin is controlled in cells. "Cell motility requires actin inside the cell to constantly be remodeled," he said.

Actin filaments can be stabilized by distinct so-called "capping" proteins that bind to the filament ends to stop further addition or loss of individual actin proteins.

S2 tethers globular myosin to the thick filament (horizontal yellow line), which stays in place while the actin filament moves. Modified from Spudich (2001).

In a paper recently published in the magazine Science, members of the Goode Laboratory, in collaboration with members of the Lab of Jeff Gelles, illustrate that actin filament assembly relies on a ...

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

Thin, flexible protein strands called actin filaments act like bones for our cells and are critical for its movement. Supercomputer simulations have helped solve a decades-old mystery of how actin ...