Here, we generated a high-resolution EPN single-cell dataset with a particular focus on the comparison ... Notably, our analysis on the sample GTE009 showed that cells from different subclones on the ...

scRNA-seq was performed on single-cell suspensions pooled from P1 and P7 cochlea duct. All samples were analyzed using canonical correlation analysis with the Seurat R package. Cells were clustered ...

R package with collection of functions created and/or curated to aid in the visualization and analysis of single-cell data using R.

Here, we report a systematic transcriptional atlas to delineate molecular and cellular heterogeneity in GA using single-cell RNA sequencing (scRNA-seq). Design We performed unbiased transcriptome-wide ...

Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma (PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune system. Here, we aimed to ...

Although IL1RL1 appears to be mast cell-specific in tSNE plots, more than ~50% of its total expression in biopsies was seen ... which is to be expected as both CPA3 and TPSB2 were specifically ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Feb. 12, 2025 — Scientists have uncovered the equipment that enables bacteria to survive exposure to antibiotics: a shuttling mechanism that helps a complex of proteins pump out a wide spectrum ...

Neural stem cells (NSCs) contribute to plasticity and repair of the adult brain. Niches harboring NSCs regulate stem cell self-renewal and differentiation. We used comprehensive and untargeted ...