They result in intervertebral disc degeneration, sciatica, chronic pain, and cerebrogenic pain. Transcriptional and post-transcriptional regulation play a role in these diseases, and involve ...

However, recent data implicate several families of transcription factors that appear critically important in the regulation of memory. For example, CREB, NF-kB, AP-1, Egr, and C/EBP families are ...

CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

Background Development of diffuse-type gastric cancer (DGC) starts with intramucosal lesions that are primarily composed of ...

Abscisic acid (ABA), a key environmental response hormone, strongly inhibits seed germination and serves as a central ...

A new study reveals that microRNAs—tiny regulators of gene expression—play a crucial role in shaping Purkinje cells, rare brain neurons linked to movement and neurodevelopmental disorders.

Glioblastoma multiforme (GBM), commonly referred to as glioblastoma, is a malignant intracranial tumor derived from glial ...

Binding of miR-3036-5p to CYP18A1 can be prevented by an A-to-I RNA editing, thus elevating CYP18A1 expression, decreasing 20E titer, and finally regulating the wing dimorphism of offspring in aphid.

Nasopharyngeal carcinoma (NPC) is a malignant tumor originating from the nasopharyngeal epithelium. Due to its concealed location and nonspecific ...

Understanding archaeal metabolic gene regulation is technically challenging ... develop a method to quantify the transcriptional dynamics of multiple metabolic genes in single cells of a ...

This Review discusses the molecular mechanisms of end resection and its regulation ... The CDK8-AHL10-SUVH2/9 module is critical for transcriptional dynamics in response to salt stress.

This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...