Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase, that ...

First, Lear's team helped to create tagged transgenic strains for more than 90% of known transcription factors in the fruit fly genome; collaborators at Yale generated tagged transgenic strains ...

Researchers have developed a novel method using CRISPR to study transcription factors affecting blood cell development. The ...

Sanofi has returned to Nurix Therapeutics for another autoimmune candidate, paying $15 million and committing up to $465 ...

Researchers discovered peptides that permanently block a key cancer protein once thought untreatable, using a new screening method to test their effectiveness inside cells. For the first time, scienti ...

Nurix DEL-AI drug discovery engine generated a drug discovery program to this previously undruggable target Nurix received a $15 million license extension fee from Sanofi under its 2019 collaboration ...

The unexpected discovery may provide scientists with new insights into how cancer develops — and how to combat it.

A recent study has shed light on the transcriptional regulatory mechanisms of Penicillium expansum, the fungal culprit behind ...

Now researchers from the University of Bath have for the first time detailed an approach to discover peptides that bind selectively and irreversibly within cells, permanently blocking a transcription ...

The detection of metastases in Merkel cell carcinoma (MCC) requires additional testing, such as pancytokeratin (panCK) or CK20, with no guarantee of success. Recent findings have identified ...

Nurix Therapeutics (NRIX) announced that Sanofi (SNY) has exclusively licensed an undisclosed Nurix program targeting a previously undruggable ...