好书推荐！《动物行为实验指南》电子版pdf，网盘发货《动物行为实验指南》共674页，涵盖了常见的实验动物，如小鼠、大鼠和斑马鱼，详细描述了每一种行为测试的实验设计、测试设备、实验流程、评估指标、预期结果、常见问题及解决方法、数据分析、模型应用与局限性 ...

where we inject human pathological tau into P301S transgenic mice. And so we want to be sure we exceed those, what the EC50, if you will, of that effect of impeding spread. And we're pretty ...

Figure 5: Age-dependent increase in insoluble tau in P301L (JNPL3) mouse brains. We have reported a transgenic mouse line, JNPL3, expressing human tau with the P301L mutation that develops NFT ...

A new study from Mass General Brigham researchers has found faster accumulation of tau-a key indicator of Alzheimer's disease-in the brains of women over the age of 70 who took menopausal hormone ...

TauRx Pharma's effort to bring a tau-targeting drug for Alzheimer's disease (AD) to market has been a marathon, with a number of setbacks over the years, but the company reckons it may finally be ...

In AD and in FTD, hyperphosphorylation of tau protein causes its misfolding and aggregation. Again, our understanding of the precise consequences of tau phosphorylation in the biology and ...

The company has advanced its VY1706 tau silencing gene therapy to IND-enabling studies and completed a single ascending dose study for its VY7523 anti-tau antibody. Despite these advancements ...

Institute of Biological Chemistry, Academia Sinica, No. 128, Sec. 2, Academia Road, Nankang, Taipei 115, Taiwan Institute of Biochemical Sciences, National Taiwan ...

Investors in TauRx Pharma have exercised warrants worth around $119 million, adding to the biotech's financial resources as it prepares regulatory filings for tau-targeting Alzheimer's drug ...

Voyager Therapeutics continues to focus on neurotherapeutics, with a particular emphasis on central nervous system (CNS) diseases such as Alzheimer’s. The company has advanced its VY1706 tau silencing ...