An oral small molecule from New York-based biotech Oligomerix curbed the tangling of tau protein in the brains of mice that ...

A study published in Brain Communications revealed new insights into early detection of Alzheimer’s disease. Researchers have ...

Figure 5: Age-dependent increase in insoluble tau in P301L (JNPL3) mouse brains. We have reported a transgenic mouse line, JNPL3, expressing human tau with the P301L mutation that develops NFT ...

Harry Potter and Back to the Future star Drew Struzan has been diagnosed with Alzheimer's disease, his wife has confirmed.

Not the Same. In amyloid-negative people (left) few tangles accumulate over a decade. In amyloid-positives (right), tangles grow faster in women (red) than men (blue). [Courtesy of Gillian Coughlan, ...

In Alzheimer's, the protein runs amok, forming tangles that have been linked to cell damage and neuronal death. Tau tangles are one of the characteristic hallmarks of Alzheimer's visible in the ...

LY3372689 was designed to slow the accumulation of hyper-phosphorylated, insoluble tau aggregates in the central nervous system, which clump together to form neurofibrillary 'tangles', one of the ...

Biomarker Test Can Detect Alzheimer's Pathology Earlier Feb. 10, 2025 — Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test can detect small ...