2025年2月6日，国家癌症中心/中国医学科学院肿瘤医院徐兵河院士等众多国内专家，在Cancer Cell上以Article形式在线发表了题为 Distinct Cellular Mechanisms Underlie Chemotherapies ...

【导读】将免疫检查点阻断疗法（ICB）与化疗相结合有望治疗三阴性乳腺癌（TNBC），但对其机理仍不完全清楚。在这项研究中，团队整合了已发表的和新的单细胞RNA测序（scRNA-seq）数据，研究了接受紫杉醇（PTX）、纳布-紫杉醇（Nab-PTX）以 ...

Newly discovered brain cells count each bite before sending the order to cease eating a meal. Columbia scientists have found specialized neurons in the brains of mice that order the animals to ...

Only cardiac muscle tissue, comprising cells called myocytes, is present in the heart. In this article, we discuss the structure and function of cardiac muscle tissue. We also cover medical ...

4 Institute of Pathology and Comprehensive Cancer Center EMN, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany Objectives CD19-targeting chimeric ...

While prokaryotic cells do not have membrane-bound structures, they do have distinct cellular regions (Figure 1). In prokaryotic cells, DNA bundles together in a region called the nucleoid. Primitive ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

Polyclonal or truly monoclonal EBV+ lymphoid B-cell proliferation will often be seen in AITL and appear to result from immunoderegulation mediated by tumor TFH-cells. Different studies demonstrate ...

Follicular T helper cells (Tfh) are a specialized subset of CD4 effector T cells that are crucial for germinal center (GC) reactions and for selecting B cells to undergo affinity maturation. Despite ...

T follicular helper (Tfh) cells participate in humoral immune by promoting inflammation and aiding B cells survival, proliferation, maturation, and generation autoantibodies. The plasticity of Tfh ...