Overview of RNA repair ... specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing) and under conditions of cellular stress ...

including binding sites for proteins, that can affect the stability of the mRNA or the efficiency of its translation. Translation Begins After the Assembly of a Complex Structure The translation ...

We show here that these diverse peptide sequences bind with comparable affinities to the Numb PTB domain at a common binding site on the surface of the protein. The NMR structure of the Numb PTB ...

In addition, approximately 85% of proteins lack specific clefts and pockets for small molecule binding. Since many proteins have similar structures, it is also not always easy to target a single ...

solving a decades-long mystery by determining the first structure of the human protein PINK1 bound to mitochondria. First discovered more than 20 years ago, PINK1 is a protein directly ...

When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA ... protein. Peptide bonds form between the adjacent amino acids to finalise the structure.