Scientists at EMBL have captured how human chromosomes fold into their signature rod shape during cell division, using a ...
But James Watson and Francis Crick's claim was a valid one, for they had in fact discovered the structure of DNA, the chemical that encodes instructions for building and replicating almost all ...
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves.
For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...
Earlier that morning, in the nearby Cavendish laboratory, the two scientists had discovered the structure of deoxyribonucleic acid, or DNA. This discovery changed the world of science and medicine ...
Members of the same species usually have DNA similar enough to have the same chromosomes and autosomes (chromosomes that don't code for sex-linked traits). In its structure, DNA contains a pattern ...
To design a DNA structure, scientists start with a desired shape or pattern and then determine the complementary DNA sequences that will allow the DNA strands to self-assemble into that structure.
In the process, DNA is transcribed into RNA and then translated into functional proteins that subsequently undergo folding to achieve their correct structure, which is key to proper function. “There ...
Those short, added pieces of DNA fold the scaffold and give it shape, acting as "staples" that hold the structure together. The technique can then be used to create shapes ranging from a map of ...
By unveiling Pol-theta's DNA-bound structure-its active state-the study provides a blueprint for designing more effective cancer drugs. We now have a much clearer picture of how Pol-theta works ...
Get Instant Summarized Text (Gist) DNA origami has been utilized to develop a technique for creating reusable, multifunctional biosensors capable of detecting proteins in bodily fluids. This ...