In prokaryotes, the circular chromosome is contained in the cytoplasm in an area called the nucleoid. In contrast, in eukaryotes, all of the cell's chromosomes are stored inside a structure called ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For ...

Thus, the 30-nanometer fiber may be highly irregular and not quite the uniform structure depicted in instructive ... 10,000:1 (depending on the chromosome). This can be thought of as akin to ...

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process ...

These motors play distinct roles in manipulating chromosome structure. Swimming motors, similar to RNA polymerases—enzymes that copy DNA sequences into RNA—help expand and contract the ...

In the multilayer chromosome model, the repetitive weak ... of the Nanoproperties of Chromatin Favoring a Multilayer ...

The ongoing major projects in the laboratory focus on the structural biology of CRISPR-Cas surveillance complexes and their suppression by anti-CRISPR proteins (in collaboration with Luciano ...