Global Antisense and RNAi therapeutics Market is valued approximately at USD 3.69 billion in 2022 and is anticipated to grow with a healthy growth rate of more than 18.72% over the forecast period ...

Discover how unique circular RNA molecules are transforming liver cancer research to combat this growing health concern.

想象一下，要在人类30亿个碱基对的基因组中，精确地测试成千上万个单一碱基突变的功能，这无异于大海捞针。传统的实验方法一次只能研究几个突变，效率极低，无法满足大规模筛选的需求。要破解同义突变之谜，首先需要一把能够高效、精准地在基因组上“动手术”的手术刀 ...

人类胚胎干细胞（Human embryonic stem cells, hESCs）存在naïve和primed两种多能性状态，二者在表观遗传、基因表达及发育潜能上存在显著差异。尽管naïve和primed hESCs间基因表达网络的差异已被广泛研究 ...

A team of Indian American scientists led by Pallavi Gopal are working to learn more about the dynamics of a protein to help ...

Skyhawk Therapeutics has dosed the first subject in the randomised Phase II/III FALCON-HD trial of the oral small-molecule ...

SKY-0515 is an oral small molecule designed to reduce the production of both huntingtin (HTT) and PMS1 proteins—two key drivers of HD pathology ...

However, so far, it has been difficult to pin down information on the structural dynamics of ADAR1 due to its size and complexity. Now, researchers led by Madhu Biyani at Kanazawa University, ...

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is it common for most RNA ...

Fred Hutch and MSK researchers showed that tumors driven by hiccups in RNA processing can't hid from the immune system. In work published in Cell, the team showed they could isolate T cells that ...

The combined results of their research, including work in mouse models, indicated that the effects of TREs interfere with a critical process called gene splicing, which is essential for gene function.

In recent years, mRNA technology enabled the rapid development of vaccines to fight COVID-19, saving millions of lives. That same mRNA-powered approach to medicine—in which synthetic mRNA is ...