WFS1 and CISD2 regulate IP3R activity through their interaction. In Wolfram syndrome, their dysfunction reduces cytosolic calcium levels, resulting in diabetes. WFS1 and CISD2 bind to IP3R and ...

The nervous system is an organ system that handles communication in the body. There are four types of nerve cells in the nervous system: sensory nerves, motor nerves, autonomic nerves and ...

A precision medicine workflow integrating proteomics and personalized xenograft models was developed and applied to an ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but ...