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生物谷
15 天
原来SR-B1在黑色素瘤里搞“小动作”!Neoplasia:SR-B1影响胆固醇代谢 ...
本研究发现黑色素瘤细胞中SR-B1缺失会诱导胆固醇合成,其通过HIF1A及S1P信号通路发挥作用。联合抑制SR-B1和胆固醇合成可增加肿瘤细胞凋亡、抑制 ...
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