As in prokaryotes, eukaryotic repressor molecules can sometimes bind to silencer elements in the vicinity of a gene and inhibit the binding, assembly, or activity of the transcription complex ...

First, pAurora2 releases the blockade of translation of the target gene on the mRNA strand, and second, the system suppresses the expression of a translation repressor. In this way, the expression ...

The operon is regulated by Lac repressor, the product of the lacI gene, which is transcribed from its own promoter (PI). The repressor inhibits transcription by binding to the lac operator (O).

Highlights from the oral presentation include: Scribe engineered novel, potent epigenetic editors (ELXRs) using newly identified repressor domains to durably and effectively silence gene ...