How do bacteria avoid wasteful production of unnecessary proteins when their genes are always on? The answer lies in regulating the operon. As trp levels increase, trp binds to trpR, causing a ...

As in prokaryotes, eukaryotic repressor molecules can sometimes bind to silencer elements in the vicinity of a gene and inhibit the binding, assembly, or activity of the transcription complex ...

First, pAurora2 releases the blockade of translation of the target gene on the mRNA strand, and second, the system suppresses the expression of a translation repressor. In this way, the expression ...

Highlights from the oral presentation include: Scribe engineered novel, potent epigenetic editors (ELXRs) using newly identified repressor domains to durably and effectively silence gene ...