SINGAPORE – A new programme has been launched in Singapore to formally study the applications of ribonucleic acid (RNA) in vaccine development, as well as in disease therapy and prevention ...

There was a nice "Aha!" moment when I realized it was the genetic material DNA undergoing the SPLICING. It's always interesting to have another layer to uncover in order to recognize the theme.

In 2022 the organizers of CASP turned their attention towards a different, yet still challenging, class of biomolecules: RNA. As with proteins, determining RNA structure typically requires costly ...

However, this approach does not address transcriptome complexity in alternative splicing and transcription termination sites; presumably further sequencing can reveal additional variants. As RNA ...

They can also be within the exon.” RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence ...

Among these are the physical and functional interactions between the transcriptional and splicing machineries that are of great importance for the generation of both canonical and alternative isoforms ...

Binding motifs for the Rbfox-family are enriched adjacent to many of the regulated exons. Endothelial deletion of Rbfox2, the only family member expressed in arterial endothelium, suppresses a subset ...