New precision genome editing technologies are transforming the therapeutic landscape for patients with certain cancers and ...

Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...

为探究 m 6 A 去甲基酶 ALKBH5 影响卵巢癌（OC）RNA 剪接的机制，研究人员开展相关研究。发现 OC 患者中 ALKBH5 高表达、m 6 A 水平降低，敲低 ALKBH5 可抑制癌细胞活力等，且明确 SRSF10 是关键靶点。该研究为 OC 的 m 6 A 修饰治疗提供新思路。

为探究单核苷酸变异（SNVs）对 COL17A1 基因剪接事件的影响，温州医科大学仁济学院等研究人员分析 703 个 SNVs，并进行迷你基因检测。结果发现 8 个候选变异中有 6 个会干扰剪接。该研究有助于精准解析 COL17A1 变异，推动个性化治疗发展。

ORNL scientists created a biosensor technology that lets researchers visualize and track RNA activity in living plants, using ...

Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, ...

ORNL scientists created a biosensor technology that lets researchers visualize and track RNA activity in living plants, using ...

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, ...