2025年1月29日,中国科学院微生物研究所邓涛研究员与高福院士团队合作在Nucleic Acids Research在线发表了题为Influenza A virus NS2 protein acts on vRNA-resident ...
Transcription is the process by which an RNA polymerase synthesizes ribonucleic acid (RNA) using deoxyribonucleic acid (DNA) as a template. 7SL is traditionally thought to function within the SRP ...
Researchers at Fred Hutch and MD Anderson discovered RNA Polymerase II on histone genes as a biomarker for cancer ...
During splicing, which occurs after transcription (i.e., the synthesis of RNA from a DNA template), the introns are removed and the exons are joined, or spliced together.
Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD Anderson Cancer Center have uncovered a biomarker capable of accurately ...
急性髓系白血病(AML)是一种常见的造血系统恶性肿瘤,其特征为未成熟白血病细胞在骨髓中的过度增殖,并伴随正常血细胞生成受阻。尽管近年来AML的治疗有所进展,但由于其高度异质性、疗效有限以及高复发率,AML患者的五年生存率依然较低。AML的病理机制研究 ...
Using a new technology and computational method, researchers have uncovered a biomarker capable of accurately predicting outcomes in meningioma brain tumors and breast cancers.
The new technology – Cleavage Under Targeted Accessible Chromatin (CUTAC) – focuses on small, fragmented DNA non-coding ...
These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...
Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...
为明确鹌鹑养殖场疾病病因,西北农林科技大学研究人员开展禽戊型肝炎病毒(HEV)相关研究,发现鹌鹑可感染 HEV 并致病。该研究丰富感染谱,为防控提供依据,推荐科研读者阅读。
为解决细菌转录终止因子 ρ 在休眠或应激时的调控机制问题,美国俄亥俄州立大学的研究人员开展核苷酸对 ρ 影响的研究。发现 ADP 和(p)ppGpp 诱导 ρ 形成无活性寡聚体。该成果为理解细菌转录调控和开发抗菌药提供新视角,值得一读。