DNA barcodes enable high throughput RNA and protein detection in deep tissue
For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the ...
Spotiphy Tool Transforms RNA Sequencing to Imaging
Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue ...
EurekAlert!7 天
cycleHCR imaging of eight protein targets in a hippocampal slice (VIDEO)
Janelia researchers developed an innovative new technique – cycleHCR -- that uses a novel DNA barcode system to track ...
Science Daily8 天
New method uses DNA barcodes for high throughput RNA and protein detection in deep tissue
The initial round of imaging uses three barcodes, picking up three RNA molecules in three different colors. These barcodes are removed, and a second round of imaging uses three different barcodes ...