Results We identified a novel RNA-binding protein, RALY (also known as hnRNPCL2), that is highly associated with colorectal tumour aggressiveness. RALY acts as a key regulatory component in the Drosha ...

Norgen’s RNA/Protein Purification Plus Kit is particularly beneficial for isolating macromolecules from precious, difficult-to-obtain, or small samples, such as biopsy materials or single foci ...

This research underscores the essential role of RNA-binding domain 3, a key portion of ADAR1, in maintaining the protein's activity and stability. Moreover, the scientist's high-resolution ...

This study reports that the RNA binding and cardiomyopathy-associated protein RBM20 is expressed in specific populations of neurons in the CNS, where it binds to and regulates the expression of ...

Transfer RNA (tRNA) is a central component of protein synthesis and plays important roles in epigenetic regulation of gene expression in tumors. tRNAs are also involved in many cell processes ...

Here, authors convincingly define the molecular determinants of cardiolipin binding ... l; lysine) and aromatic (w; tryptophan, y; tyrosine) residues that interact with cdl. (c) gfp-thermal shift ...

Introduction: Vaccines developed using modified messenger RNA (mRNA) technology show robust efficacy against severe acute ... Methods: Here, we designed a bivalent mRNA vaccine, RBDco, based on the ...

Institute of Biological Chemistry, Academia Sinica, No. 128, Sec. 2, Academia Road, Nankang, Taipei 115, Taiwan Institute of Biochemical Sciences, National Taiwan ...

We determined all rate constants of these two pathways for lactose binding to the protein galectin-3. Even though galectin-3 exists in a preestablished equilibrium of low- and high-affinity ...