Scientists just inserted a human gene into mice, and the results are nothing short of mind-blowing. The vocalizations of the ...

A study identifies a genetic link between autism and myotonic dystrophy type 1 (DM1). Researchers found that tandem repeat ...

本研究针对动脉粥样硬化中血管内皮细胞(VECs)损伤机制不明的关键问题，研究人员揭示了RNA结合蛋白IGF2BP3通过特异性结合乳酸脱氢酶A(LDHA)的3'UTR区域稳定其mRNA，从而逆转氧化低密度脂蛋白(ox-LDL)导致的糖代谢抑制，显著减轻内皮细胞凋亡。该发现为心血管疾病 ...

Deep learning-based in silico modeling (Damayanti et al, 2024) suggested new protein structures and changes in conformation of TFE3 fusion proteins with increased potential for binding DNA, RNA, and ...

Through yet unknown mechanisms, (m)RNA fragments by themselves or in association with RNA-binding proteins translocate to the nucleus, if necessary, where they modulate gene expression. Created with ...

We determined all rate constants of these two pathways for lactose binding to the protein galectin-3. Even though galectin-3 exists in a preestablished equilibrium of low- and high-affinity ...

NOVA1- an RNA-binding protein in the brain that regulates neural ... head of the Laboratory of Molecular Neuro-Oncology. “NOVA1 may be a bona fide human ‘language gene,’ though certainly ...

This study reports that the RNA binding and cardiomyopathy-associated protein RBM20 is expressed in specific populations of neurons in the CNS, where it binds to and regulates the expression of ...