unfolded protein response). RNA cleavage can occur either: (i) by a transesterification mechanism that yields 2’,3’-cyclic-PO 4 and 5’-OH ends; or (ii) via a hydrolytic mechanism that leaves 3’-OH and ...

A new study conducted by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National ...

Researchers have discovered that 'DEAD-box helicases 54 (DDX54)', a type of RNA-binding protein, is the master regulator that hinders the effectiveness of immunotherapy -- opening a new path for lung ...

Researchers have identified cellular factors that regulate the delivery and stability of mRNA to expand the potential of mRNA ...

Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how ...

Enter the anti-CRISPR protein AcrVIB1 ... The simpler and therefore initially expected mechanism would have been to just prevent the guide RNA from binding in the first place," says first author ...

Binding of miR-3036-5p to CYP18A1 can be prevented by an A-to-I RNA editing, thus elevating CYP18A1 expression, decreasing 20E titer, and finally regulating the wing dimorphism of offspring in aphid.

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions like a film editor rearranging scenes from the same footage to create ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science ...