A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, suggesting it as a potential therapeutic target.

By integrating metabolomic, transcriptomic and epigenomic data, we identified metabolic alternations, especially cysteine-associated pathways, accompanied with the epigenetic changes during the ...

However, several Trp metabolism end-products are essential to intestinal homeostasis. Here, we investigated the role of metabolites from the kynurenine pathway. Design Targeted quantitative ...

Skeels using metabolomics and transcriptomics. It aims to identify metabolic pathways and differentially expressed genes related to flavonoids and anthocyanins biosynthesis. Results: The PP (purple ...

Therefore, the knockdown of SLC25A1 or ACLY does not appear to affect the myristoylation of FSP1. Further linking the inhibition of the SLC25A1/ACLY-FSP1 pathway to cancer, we investigated the effect ...

Researchers are able to test in parallel the effects of over 1500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown mechanisms for known medications.

Metabolism often flies under the radar when designing a fat loss transformation program. A balanced 30-minute training session can boost your metabolism for up to 14 hours, which can be a game-changer ...