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结构变异在基因组中广泛存在,但其复杂性及其在反复驱动局部适应中的作用尚不明确。在这项研究中,我们利用单倍型基因组组装技术,揭示了竹节虫隐色模式的适应性分化是由反复出现结构变异所驱动的,而非简单染色体倒位。
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Glow-in-the-Dark Sharks & Other Fascinating Bioluminescent FishYou know those little glow-in-the-dark stars that dot the ceilings of children’s rooms? Yeah, I didn’t have stars. Instead, I ...
为探索胃癌(GC)预后生物标志物及发病机制,研究人员分析转录组测序数据。发现 25 个未报道基因,其中 ADAMTSL2 是 GC 预后独立预测因子,或参与 Notch 信号通路。为 GC 诊断、预后评估及治疗提供新方向。
急性肺损伤(ALI)病因多样,其共享遗传特征不明。研究人员通过整合不同病因 ALI 转录组展开研究,发现 Slc7a11 是共享铁死亡相关瓶颈基因,且在不同病因 ALI 中表达上调。这有助于理解 ALI 的共享分子机制。
New research finds reduced ELOVL2 enzyme activity speeds up immune cell aging and disrupts genes linked to cancer.
New research suggests that decreased activity of ELOVL2 -- a key enzyme in lipid metabolism -- accelerates white blood cell aging and alters genes associated with the onset of blood cancers.
A new study provides solutions to the pressing need to identify factors that influence Alzheimer's disease (AD) risk or resistance while providing an avenue to explore potential biological markers and ...
Munich news, health insurance, technology, jobs and other topics for expatriates. The Eye Newspapers covers daily news and offers services for foreigners.
A recent review published in Genes & Diseases sheds light on the complex and multifaceted role of RNA-binding proteins (RBPs) in cancer progression, ...
Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact ...
Indian scientists, in collaboration with global experts from NASA and the European Space Agency, have pitched to do seven ...
Evidence suggests that in Parkinson’s disease, a breakdown in lysosomal function allows lipids to build up within cells. Variants of the GBA1 gene, the strongest genetic risk factor for sporadic PD, ...
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