While it is accepted that extracellular vesicles (EVs)-mediated transfer of microRNAs contributes to intercellular communication, the knowledge about molecular mechanisms controlling the selective and ...

Tau protein is essential for microtubule stability and neuronal function. The protein’s disfunction is linked to several ...

These properties make SA invaluable in biomolecule capture and enrichment in analytical applications such as ELISA, protein ...

A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and ...

In S. Cerevisiae, meiotic stress granules (SGs) form at temperatures ~10°C lower than those in mitosis, seeded by the meiosis-specific RNA-binding protein Rim4. These SGs halt meiosis and ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Chronic kidney disease (CKD) is typically associated with severe fibrosis, the exact pathogenesis of which remains unclear.