Scientists see several important uses for staging. For example, it can steer people more precisely to appropriate treatments.

综合上述研究，NDP52 GE 作为 NDP52 的一种变体，在对抗 AD 方面展现出了巨大的潜力。它能够通过自噬更有效地清除病理性 TAU，减轻神经毒性，并且在遗传层面上与降低 AD 易感性相关。这一研究为 AD 的治疗提供了全新的潜在靶点，有望推动开发基于 NDP52 GE 的创新治疗方法，如基因治疗等。不过，目前仍有一些问题有待进一步研究，例如 NDP52 GE ...

Scientists have discovered a new protein pathway involved in neurodegeneration by studying “mini-brain” organoids made from ...

GT-02287 oral presentation demonstrates new evidence of disease-modifying capacity in GBA1 and idiopathic Parkinson’s disease models Enrollment update provided for Phase 1b study Phase 1b study ...

But the new study found that having a father with the neurodegenerative disease may be tied to a greater spread of the tau protein in the brain that is a warning sign of Alzheimer’s. The ...

Several biomarkers of disease progression, including aggregated α-synuclein, IRE-1 (a marker of ER stress), LAMP-1 (a marker of lysosomal integrity), Miro1 (a marker of damaged mitochondrial destined ...

Developed by Singaporean company TauRx Pharmaceutics Ltd, the scientists based in Aberdeen report that hydromethylthionine mesylate (HMTM) could be the first oral treatment for Alzheimer’s disease (AD ...

The new study found having a father with the neurodegenerative disease may be tied to a greater spread of the tau protein in the brain that is a warning sign of Alzheimer's. It was also found that ...

The study also showed that female participants may be more at risk of a heavier buildup of tau protein than male participants. “We were surprised to see that people with a father with Alzheimer ...