The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

Background and Objective: Narcotic analgesics such as hydromorphone undergo an extensive first-pass effect resulting in a low systemic bioavailability following oral administration. Alternative ...

The pharmacokinetics, safety, and tolerability of four topical lidocaine patches 5% continuously applied for 72 hours and changed every 12 or 24 hours were examined. In this randomized ...

Quantification and prediction of human fetal (-)-Δ 9-tetrahydrocannabinol/(±)-11-OH-Δ 9-tetrahydrocannabinol exposure during pregnancy to inform fetal cannabis ...

One clinical trial site activatedPatient enrollment expected in AprilTrial designed to evaluate safety, pharmacokinetics and pharmacodynamics, of ...

On Tuesday, Adial Pharmaceuticals Inc (NASDAQ:ADIL) announced the progression to the second cohort in the pharmacokinetics study of AD04. AD04 is the company’s lead investigational genetically ...

Developing new drugs to treat illnesses has typically been a slow and expensive process. However, a team of researchers at ...

The first patient has been dosed in a phase 1 clinical trial of CT-95 among patients with mesothelin-expressing solid tumors.

Merck has shared data from the pivotal Phase 3 trial evaluating the subcutaneous administration of pembrolizumab together ...

A groundbreaking Phase 1 study suggests that once-yearly intramuscular lenacapavir could be a promising option for HIV PrEP.