Hence, understanding the role of a given molecule or pathway in immune system function ... on a high-throughput scale (serial analysis of gene expression) or have yet to be proven reliable for ...

Research team developed PathActMarker, a software package for pathway activity inference and analysis. It preprocesses gene expression data, converts it into pathway activity matrices using eight ...

The global birthrate has been in significant decline for decades. In the U.S., couples are deciding to have children later in ...

The study is useful for advancing spatial transcriptomics through its novel regression-based linear model (glmSMA) that integrates single-cell RNA-seq with spatial reference atlases, though its ...

Researchers have identified a key pathway that links how neurons send ... that connects local synaptic activity to the ...

This process of protein synthesis occurs in two stages - transcription and translation. When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA).

Chickens treated to inhibit the sonic hedgehog (Shh) pathway during development grow feathers that resemble ancient ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional elongation enzymes during gene expression, findings that may inform the ...

Cell Analysis of Debrided Diabetic Foot Ulcers Reveals Dysregulated Wound Healing Environment in Non-Hispanic Black Patients,” published in the March 2025 issue of Journal of Investigative Dermatology ...