Chickens treated to inhibit the sonic hedgehog (Shh) pathway during development grow feathers that resemble ancient ...

Americans pay a lot of money for prescription medications. In 2023, spending on prescription drugs in the United States ...

Variant, a company dedicated to developing innovative treatments for orphan inherited eye diseases, and the Rare Ocular Diseases Center at the University of Campania Luigi Vanvitelli (UCLV) in Naples ...

These data suggest PI3 kinase/mTOR signalling is an important component in TGF-β 1 induced αSMA and collagen gene expression and that an mTOR dependent, Akt independent pathway mediates this ...

Community-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc.

Research team developed PathActMarker, a software package for pathway activity inference and analysis. It preprocesses gene ...

Conclusions ER stress in hepatocytes induces PHLDA3 via IRE1–Xbp1s pathway, which facilitates liver injury by inhibiting Akt ... unravelled the new functional role of PHLDA3 in the event of hepatocyte ...

The following is a summary of “Spesolimab Reduces Inflammation in Generalized Pustular Psoriasis: Molecular Characterization ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Results: Our analysis implicated LRP1B as a tumor suppressor gene. Experimental results confirmed that LRP1B expression was reduced in CRC and its knockdown was associated with poor prognosis.

BioSciences announced the first patient has been dosed in the Phase 2 ASCEND study of PCRX-201 for the treatment of ...