Background Best current estimates of neuropathic pain (NeuP) prevalence come from studies using various screening detecting pain with probable neuropathic features; the proportion experiencing ...

However, its pathogenesis is still poorly understood ... The genetic and protein alterations that underlie the development of neuropathic pain. Following nerve injury, a series of changes occurring in ...

Neuropathic pain syndromes remain a major therapeutic challenge, despite considerable research efforts during the past few decades. Many hypotheses about the mechanisms of pain generation have ...

Pain is one of the most debilitating symptoms that presents with neuropathy. Neuropathic pain syndrome is a challenge to treat and, even with appropriate evidence-based treatment, only a 40% ...

A painkiller developed by Germany's Algiax Pharma has shown efficacy in the treatment of chronic neuropathic pain, another positive development in the search for alternatives to opioids.