is a major factor in multiple animal models of neuropathic pain, encompassing those due to drug-induced peripheral nerves, diabetes-induced neuropathy, and chronic constriction injury. This ...

Pain signals originating in the body’s periphery are conveyed to the brain along a relay of neurons in four different parts of the ascending sensory pathway: the dorsal root ganglion, dorsal ...

Chronic pain is defined as pain that persists beyond acute pain, typically over six months. It can be initiated with an injury or disease, but may persist after the triggering injury has healed.

Stanford researchers have recreated a key human pain-sensing nerve circuit in a lab dish, using fused mini-organoids that mimic the ascending sensory pathway from skin to brain. This breakthrough ...

Unexplained itching with no visible rash is more common than you think. Learn how your brain and nerves play a role in the ...

Summary: Researchers have recreated the human ascending sensory pathway in a lab dish, using organoids that model the key brain and spinal cord regions responsible for transmitting pain. This ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...