That may be because most mouse models of Alzheimer's disease harbor the Swedish mutation. This has so far hindered efforts to study the beneficial effects of the Icelandic mutation.

Researchers have developed the first mouse model for a mitochondrial tRNALeu mutation, showing that the associated metabolic disorder results from faulty RNA processing. Studying the role of ...

Endothelial NOS expression was compared in control and iNOS-transduced cells grown in the presence or absence of a selective iNOS inhibitor, L-N6- (1-iminoethyl) lysine hydrochloride (L-NIL).

Mutations in a critical gene that controls heart and blood vessel development in mouse embryos mimics a type of congenital heart disease in humans, according to new research by researchers at the ...

02-006 - MPS IVa (Morquio A) mouse with point mutation and tolerant of human GALNS. In this section . Researchers. Shunji Tomatsu. Summary. A MPS Iva (Morquio A) mouse with a point mutation (Cys79Ser) ...

Image of the mouse lung showing endothelial cells lining the blood vessels in red and nuclei of the cells in blue. Air spaces are the dark areas of the image. The cyan and yellow marks show AHR ...

Nature Medicine - p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells Skip to main content Thank you for visiting nature.com.

More information: Haruna Tani et al, Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNALeu(UUR) with a ...

Using their new mouse model, the team discovered how the Icelandic mutation protects mice against Alzheimer’s disease. Specifically, they found that the Icelandic mutation decreases the susceptibility ...