2 Since 1986, over 117 monoclonal antibodies have been FDA-approved, beginning with the mouse monoclonal antibody Muromonab-CD3 for kidney transplant rejection. 3 In additional to antibodies from mice ...

Both methods combine antibody-oligonucleotides with existing single-cell RNA-sequencing (scRNA-seq ... and 13 cell-surface proteins of human and mouse immune cells. They showed that CITE-seq ...

Map of pathological tau detected by AT8 antibody staining in MAPTInt10+3 and MAPTS305N;Int10+3 mice. Credit: Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01829-7 ...

Researchers say they are exploring therapeutic options to block fatty acid accumulation and immunosuppressive signals between ...

A comprehensive proteomic map of liver fibrosis progression and healing in two mouse models identifies etiology-specific extracellular matrix components, laying the foundation for targeted ...