Their study, published in Communications Biology, investigated the role of mitochondrial transcription elongation factor (TEFM) using genome editing techniques in cultured human cells. Although ...

Copper (Cu) is essential for brain development and function, yet its overload induces neuronal damage and contributes to neurodegeneration and other neurological disorders. Multiple studies ...

The mitochondrial genome is the full genetic complement of a mitochondrion. Mitochondrial DNA is only a small portion of the total DNA of a eukaryotic cell and in most species is solely inherited ...

Ring-shaped extrachromosomal DNA is implicated in many cancers. Rachel Brazil talks to the scientists trying to uncover their ...

Critically, augmenting mitochondrial ROS with MitoParaquat blunted the beneficial effects of Nrf3 deletion on cardiac function and remodeling. Mechanistically, a redox regulator Pitx2 (paired-like ...

Inga Rødahl from the Center for Infectious Medicine (CIM) at the Department of Medicine, Huddinge (MedH) is defending her ...

The anti-melanogenesis effect of ligustroside derived from Ligustrum japonicum and its underlying mechanisms are explored.

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...