Psychiatric disorders challenge us deeply. At the University of Arizona, researchers dissect their molecular roots, focusing ...

This analysis revealed several miRNAs with specific expression patterns, such as: osa-miR528-5p was detected exclusively in the blood of adult male giant pandas. The biological processes enriched in ...

This review highlights the miRNA-mRNA target networks essential for chondrocyte differentiation ... Moreover, many miRNAs exhibit preferential expression in specific growth plate zones (Figure 2), ...

The aim of the study was to perform a tissue-specific miRNA profile and, based on this, to examine the function of miRNA-145 in the oesophagus. Design miRNA expression profiling using microarray ...

RNA-based therapeutics are gaining traction due to advancements in delivery technologies, despite historical challenges with ...

for specific delivery of anti-miRNA 138. Results: Our results suggested that the 3WJ-M4-LNA nanoparticles, not 3WJ-M4 or 3WJ-LNA, can specifically deliver anti-miRNA to MSCs, resulting in significant ...

Intriguingly, the miRNA miR-8055, partially investigated ... challenges due to their low expression levels, tissue-specific ...

RALY acts as a key regulatory component in the Drosha complex, and promotes the post-transcriptional processing of a specific subset of miRNAs (miR-483, miR-676 and miR-877). These miRNAs ...

bMIND is a Bayesian deconvolution method to integrate bulk and scRNA-seq data. With a prior derived from scRNA-seq data, we estimate cell-type-specific (CTS) expression from bulk tissue expression via ...

The Cancer Genome Explorer (TCGEx) is a web-based interface that simplifies the analysis of cancer gene expression data from multiple sources ... In each module, the user can further focus on specific ...