Malignant hyperthermia (MH): A pharmacogenetic disorder of skeletal muscle triggered by certain anaesthetic agents, leading to a hypermetabolic state and potentially fatal complications.

1 Introduction. Malignant hyperthermia (MH) is a rare but potentially life-threatening autosomal dominant disorder triggered by certain anesthetic agents, leading to uncontrolled hypermetabolism in ...

Malignant Hyperthermia is a rare but life-threatening condition, stemming from a reaction to certain medications such as succinylcholine and certain anesthetic medications. Up to 700 cases are ...

Explores how inhalational anesthetics trigger general anesthesia through interaction with calcium channel RyR1.

Since their effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general ...

Background "Neuroleptic malignant syndrome" (NMS) derives from the French "syndrome malin des neuroleptiques" and was first described in 1960 by Delay [] and colleagues in association with ...

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for ...

An attorney representing the family of Payton, the 14-year-old Marshall Middle School student who collapsed and died last ...

A research team at The University of Tokyo has discovered that inhalational anesthetics activate a protein called type 1 ryanodine receptor (RyR1), ...

The former Houston ISD middle school student who died on campus in August may have been genetically predisposed to some conditions linked to sudden death, but no cause of death could be found with ...

(*1) Malignant hyperthermia. Life-threatening elevation in body temperature that occurs during general anesthesia. It occurs in patients with genetic predisposition (frequently RyR1 mutation) when ...

Not all brain tumours are cancerous! Understand the key differences between benign and malignant brain tumours. Learn from an expert about the symptoms, diagnosis, and treatment options for both ...