The Warburg effect, which was first described a century ago, asserts that mitotic tumor cells generate higher quantities of lactate. Intriguingly, even in typical physiological circumstances, ...

Our HS sports photos like the ones above put you right up close with the action and the whole experience. Check them out by clicking anywhere in the collage above to open the photo gallery. Don ...

黏着斑激酶通过调节肝星状细胞有氧糖酵解诱导肝纤维化研究解读 贵州医科大学附属医院感染病科的研究人员陶黄、周明宇、邹高亮等人在《Scientific Reports》期刊上发表了题为 “Focal adhesion kinase promotes aerobic glycolysis in hepatic stellate cells via the cyclin D1/cMyc/MCT-1 ...

The main regulators of this metabolic shift are the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinase (PDK) isoforms 1–4. PDK is known to be overexpressed in several cancers and is ...

ES-2/GFP cells were cultured in McCoy’s 5A medium supplemented with 10% FBS, 0.1% sodium pyruvate, and 1% penicillin/streptomycin. Cells were revived from working cell banks in which cells in ...

The screen provides a wealth of information that will be of interest to cell cycle and cancer biologists. Convincing evidence is provided that resistance to palbociclib can result from loss of PRC2.1 ...

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Busà Photography / Getty Images Many people believe that being wealthy means having a nice house, a late-model car, and a summer cottage, but the kind of money possessed by the wealthiest 1% of ...

Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...

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