Photoimmunotherapy with the M@P nanoplatform offers a novel approach, triggering cancer cell death and boosting immune ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...

Developing low side-effect pyroptosis and ferroptosis inducers for cancer therapy, especially dual function inducers, is a ...

Researchers developed a coordination n (ZnDHT NM) that targets tumor cells and cancer stem-like cells, enhancing cancer ...

Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradatio ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

The protein Spns1 helps transport fat molecules out of lysosomes, preventing harmful buildup and offering insights for rare ...

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...

The whole P-cadherin/antibody/drug complex is then sent to a structure called the lysosome to be broken down. "Our results establish an outside-in signaling mechanism that provides fundamental ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...