Hepatocellular carcinoma (HCC) is considered the second most deadly cancer worldwide ... in aberrant activation of the Wnt signaling pathway. Analogous mechanisms have also been identified in other ...

Pancreatic cancer has a high potential for spreading metastasis to other organs. Proliferation and migration of pancreatic ductal adenocarcinoma (PDAC) cells are enhanced through upregulating various ...

A recent study published in the Journal of Clinical Investigation by researchers at Johns Hopkins University School of Medicine and collaborators identified HMGA1 as a key epigenetic regulator that ...

1Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng, China.

We explore the therapeutic potential of targeting proapelin cleavage sites in metastatic colorectal cancer by introducing ... malignant and metastatic phenotype of cancer cells and angiogenesis ...

We explore the therapeutic potential of targeting proapelin cleavage sites in metastatic ... cancer cells and angiogenesis through modulation of apelin receptor dynamics, affinity, internalization, ...

Colorectal cancer (CRC) is a highly heterogeneous malignant disease that can metastasise to lymph node, liver ... of CRC liver and ovarian metastasis. Malignant cells with high delta-like ligand 4 ...

N1 Single lymph node metastasis ... Detecting cancer cells in the bloodstream is expected to provide great information about metastatic potential and response to systemic therapy.

nenetus – stock.adobe.com Colorectal cancer occurs when cells in the colon or rectum grow out of control, creating tumors that can spread to the rest of the body if left untreated. Though people ...

Scientists from the University of Sharjah have found that a naturally growing aromatic plant contains ingredients with the ability to treat colorectal ... pathway, which plays a major role in ...