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生物通
21 天
解锁辐射生物学新密码:从核纤层蛋白 A 探寻辐射反应与疾病关联的 ...
这进一步支持了辐射损伤 lamin A 的观点。 2. 积累的核纤层蛋白 A 减缓 ATM 核穿梭 当 lamin A 的半胱氨酸残基受损后,会带来一系列连锁反应。首先,lamin A 与 DNA 的结合能力可能会丧失,而且它在细胞核质中的分布也会发生改变。这会对 ATM 蛋白的核穿梭产生影响 ...
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