C&EN29 天
Use of Aldehyde–Alkyne–Amine Couplings to Generate Medicinal Chemistry-Relevant Linkers
Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Falmer BN1 9QJ, U.K. Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, 1 James ...
Frontiers6 年
Family-Four Aldehyde Dehydrogenases Play an Indispensable Role in the Pathogenesis of ...
These free radicals including reactive oxygen species (ROS) serve as a substrate for generating reactive aldehydes. The accumulation of free fatty acid radicals, ROS, and reactive aldehydes in cell ...
Frontiers9 年
Exploring the conformational landscape of menthol, menthone, and isomenthone: a microwave study
The program identifies and fits the different species within a spectrum using calculated ab initio rotational constants as initial input values. Menthone [2-isopropyl-5-methylcyclohexanone, 97% purity ...