Bacterial insertion sequences (IS) are small DNA segments (<2.5 kb) with a simple genetic organization. Most IS elements exhibit short terminal inverted repeat sequences (IR) and encode a transposase, ...

测序数据经严格清洗后，用 CLC Genomics Workbench 12 软件进行组装。运用多种生物信息学软件，如 MLST 2、ResFinder 4.1、Integron_finder 等，进行多位点序列分型（MLST，Multilocus Sequence Typing）、耐药基因鉴定和 I 类整合子注释等分析。 统计分析：采用卡方检验评估分类变量 ...

Sewage monitoring – a new, resource-efficient method for population-based surveillance of antibiotic resistance The project is funded by the Wellcome Trust (10.2 MSEK) for the period 2022-2025. The ...